1986年,在澳大利亚和美国用α_2干扰素滴鼻预防普通感冒的报道中,所用干扰素的剂量为5×10~6Iu/天,于某家庭首例患者发病后,其他成员连续滴鼻7天。结果发现,澳大利亚受试者和美国受试者普通感冒发病率分别减少41％和39％。澳大利亚组用干扰素后,普通感冒病程缩短76％(由6.3天减至1.5天),但对所有其他呼吸道疾病病程 In 1986, in Australia and the United States with alpha 2 interferon nasal drops to prevent the common cold reported interferon dose of 5 × 10 ~ 6Iu / day, in the first case of a family after the onset of disease, other members of the continuous nasal dripping 7 days . The results showed that the prevalence of the common cold in Australian subjects and U.S. subjects decreased by 41% and 39%, respectively. In Australia with IFN, the duration of the common cold was shortened by 76% (from 6.3 days to 1.5 days), but for all other respiratory disease durations