双心医学研究成果提示心血管疾病和精神心理疾病常易合并发生,因此他汀类药物和抗抑郁药物联合应用的机会增加。两种药物相互作用所导致的他汀不良反应报道也日渐增多。本文综合分析回顾相关文献,从药物相互作用角度介绍了两类药物联用引起不良反应的相关机制和正确的联合用药方法。 Bicynodyne medical research results suggest that cardiovascular disease and mental disorders are often complicated by the merger, so statins and antidepressants have increased the chance of joint use. The two drugs caused by the interaction of statin adverse reactions are also increasing reports. In this paper, a comprehensive review of the relevant literature review, from the perspective of drug interactions introduced two types of drug-induced adverse reactions associated with the mechanism and the correct combination of drugs.