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应用国产盐酸米托蒽醌注射液单药和组成联合化疗方案治疗各类恶性肿瘤230例,在可评定疗效的218例中,白血病单药有效率43.8％,联合化疗有效率81.8％;恶性淋巴瘤单药有效率61％,联合化疗有效率65.5％;乳腺癌单药有效率34.6％,联合化疗有效率50％。主要毒副作用是白细胞减少,未见严重的心脏毒性。我们认为米托蒽醌是一有效的、值得临床推广应用的抗肿瘤药。
The application of domestic mitoxantrone injection single and combination chemotherapy in the treatment of 230 cases of various types of malignant tumors, curative effect can be assessed in 218 cases, leukemia single drug effective rate of 43.8%, combined with chemotherapy, the effective rate of 81.8%; malignant lymph Tumor single drug effective rate of 61%, 65.5% of the combined chemotherapy; breast effective rate of single drug 34.6%, 50% of the combined chemotherapy. The main side effects are leukopenia, no serious cardiotoxicity. We believe that mitoxantrone is an effective antitumor drug worthy of clinical application.