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目的分析2011年内蒙古自治区(内蒙古)疑似预防接种异常反应(adverse events following immunization,AEFI)的发生特征,评价内蒙古AEFI监测系统运转状况。方法通过疑似预防接种异常反应监测信息管理系统收集2011年内蒙古报告的AEFI个案数据,采用Excel软件进行统计分析,以描述性方法进行流行病学分析。结果2011年内蒙古共报告AEFI 594例,男性多于女性,性别比为1.22∶1;一般反应547例,占92.09%,异常反应37例,占6.23%;4-7、10-12月为发病高峰期;0岁组报告最多为220例,占37.04%;百白破疫苗AEFI报告最多为238例,占40.07%;接种后1 d内发生AEFI 493例,占83%;48 h内报告率为85.86%,48 h内调查率为98.04%。结论监测系统运行良好,2011年灵敏度较2010年明显上升;48 h内报告率有待提高。
Objective To analyze the occurrence characteristics of suspected AEFI in Inner Mongolia Autonomous Region (Inner Mongolia Autonomous Region) in 2011 and evaluate the operation status of AEFI monitoring system in Inner Mongolia. Methods The data of AEFI cases reported in Inner Mongolia in 2011 were collected through the information management system of suspected antivirus reaction monitoring information, and the data were analyzed by Excel software. The descriptive method was used for epidemiological analysis. Results A total of 594 AEFI patients were reported in Inner Mongolia in 2011, with more males than females, with a sex ratio of 1.22:1. 547 cases were common reactions (92.09%), 37 cases were abnormal reactions (6.23%), 4-7 months and 10-12 months The peak of 0-year-old group reported up to 220 cases, accounting for 37.04%; the maximum of AEFI report of diphtheria-pertussis vaccine was 238 cases, accounting for 40.07%; 493 cases of AEFI occurred within 1 d after inoculation, accounting for 83% For 85.86%, within 48 h, the investigation rate was 98.04%. Conclusion The monitoring system is operating well and the sensitivity in 2011 increased significantly compared with that in 2010. The reporting rate needs to be improved within 48 h.