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目的:探讨黄体中期子宫内膜轻创对下一个周期冷冻胚胎移植妊娠结局的影响。方法:回顾性分析进行冷冻胚胎移植的143例患者的临床资料,其中29个周期黄体中期行子宫内膜轻创(轻创组),114个FET周期未行此项干预(对照组),比较两组的妊娠结局。结果:轻创组临床妊娠率为62.07%,对照组临床妊娠率为44.35%,前者有明显的增高趋势,但无统计学差异。对照组中自然周期准备内膜(n=70)和人工周期准备内膜(n=44)的临床妊娠率分别是48.57%和38.64%,两者相比无统计学差异。结论:对于反复种植失败的患者于FET的前一个周期的黄体中期轻创子宫内膜可以在一定程度上提高临床妊娠率。FET时自然周期和人工周期准备内膜其临床妊娠率无明显差异。
Objective: To investigate the effect of mid-luteal endometrial minimally invasive surgery on pregnancy outcomes in the next cycle of frozen embryo transfer. Methods: The clinical data of 143 patients who underwent frozen embryo transfer were retrospectively analyzed. The endometrial minimally invasive (minimally invasive group) was performed in 29 cycles of luteal phase, and 114 FET cycles were excluded from this intervention (control group). Two groups of pregnancy outcomes. Results: The clinical pregnancy rate was 62.07% in the minimally invasive group and that in the control group was 44.35%. The former had a significant increase trend but no significant difference. In the control group, the clinical pregnancy rates for preparation of intima (n = 70) and artificial period (n = 44) in the natural cycle were 48.57% and 38.64%, respectively, with no significant difference between the two groups. Conclusions: Mild luteinizing endometrium in the first cycle of FET in patients with repeated implant failure may improve the clinical pregnancy rate to a certain extent. There was no significant difference in the clinical pregnancy rate when the natural period and artificial period of FET were prepared.