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用自制纯化牛硬脊膜内马尾神经根Ｐ２蛋白作为抗原，诱导家兔产生慢性复发性实验性变态反应性神经炎（ｃｒＥＡＮ），通过观察临床表现、电生理学、病理学改变，发现与人类慢性格林－巴利综合征（ｃＧＢＳ）相似，提示ｃＧＢＳ和ｃｒＥＡＮ的发病与针对Ｐ２蛋白的自身免疫反应有关
Purified bovine spinal endometrial root P2 protein was used as antigen to induce chronic recurrent experimental allergic neuritis (crEng) in rabbits. By observing the clinical manifestations, electrophysiological and pathological changes, we found that chronic sinusitis Similar to Green-Barre syndrome (cGBS), suggesting that the pathogenesis of cGBS and crEAN is related to the autoimmune response to the P2 protein