特拉唑嗪是新的长效α_1受体阻滞剂。其作用类似哌唑嗪,但T_(1/2)是后者的4倍,每日服药1次即可。水溶性比哌唑嗪强28倍,可作静脉注射。剂量一般为1-5mg(少数为20mg),qd,首剂从小剂量开始。对轻、中度高血压病人的卧位收缩压和舒张压均明显降低(分别下降1.6-1.73和1.6-2.0kPa);可长期治疗。副作用轻微,且有降低TC和LDL-ch、升高HDL-ch的作用。 Terazosin is a new long-acting alpha 1 receptor blocker. Its role is similar to prazosin, but T_ (1/2) is 4 times the latter, once daily medication can be. Water-soluble than prazosin 28 times stronger, for intravenous injection. The dose is generally 1-5mg (a few of 20mg), qd, the first dose from the beginning of a small dose. On mild and moderate hypertension in patients with lying position systolic and diastolic blood pressure were significantly lower (decreased 1.6-1.73 and 1.6-2.0kPa, respectively); long-term treatment. Minor side effects, and lower TC and LDL-ch, HDL-ch increased role.