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近年来,许多研究者发现自身免疫反应在扩张型心肌病(DCM)的发生发展上起重要作用;并注意到病毒性心肌炎与 DCM自身免疫现象的密切关系。本文就此方面,作一综述。一、自身免疫在 DCM 发病上的重要作用1.抑制性 T 淋巴细胞数量及功能缺陷:目前认为,自身免疫性疾病的发病机理是:在机体免疫调节紊乱的前提下,通过 T细胞旁路激活及独特型——抗独特型抗体的旁路机制,在清除抗原中损害自身组织,形
In recent years, many researchers have found that autoimmune reaction plays an important role in the development of DCM and noted the close relationship between viral myocarditis and DCM autoimmune phenomenon. This article in this regard, make a summary. First, the important role of autoimmune in the pathogenesis of DCM 1. Inhibit the number of T lymphocytes and functional defects: It is currently believed that the pathogenesis of autoimmune diseases is: under the premise of the body’s immune regulation disorders, activated by T-cell bypass And unique type - anti-idiotypic antibody by-pass mechanism, in the removal of antigen damage to their own organizations,