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目的分析新生儿肺炎抗生素相关性腹泻的发病率,评价使用微生态制剂妈咪爱的干预作用。方法选取2011年1月至3月新生儿肺炎患儿146例为对照组,选取2012年4月至6月新生儿肺炎患儿158例为治疗组。2组均按新生儿肺炎给予抗生素等常规治疗,若出现腹泻,给予蒙脱石散口服及补液等治疗,治疗组在此基础上加用妈咪爱口服。观察微生态制剂妈咪爱对抗生素相关性腹泻的干预作用。结果使用妈咪爱后,治疗组抗生素相关性腹泻的发生率较对照组下降(5.7%vs20.5%,χ2=14.97,P<0.01),平均住院天数较对照组减少[(6.9±1.4)vs(9.1±2.1)d,t=17.48,P<0.01],均未发生不良反应。结论对新生儿肺炎抗生素相关性腹泻辅之以微生态制剂,可有效减少抗生素相关性腹泻的发生率、减轻腹泻程度、减少住院时间。
Objective To analyze the incidence of antibiotic-associated diarrhea in neonatal pneumonia and to evaluate the intervention effect of probiotics using mommy. Methods A total of 146 neonates with pneumonia were selected as the control group from January to March 2011. 158 children with neonatal pneumonia were selected as the treatment group from April 2012 to June 2012. Both groups were given routine antibiotics and other neonatal pneumonia treatment, if diarrhea, montmorillonite given oral and rehydration therapy, the treatment group on the basis of this plus Mommy love oral. To observe the intervention effect of probiotics mommy on antibiotic-associated diarrhea. Results Compared with the control group, the incidence of antibiotic-associated diarrhea in the treatment group decreased by 5.7% vs20.5% (χ2 = 14.97, P <0.01) and the average number of days of hospitalization decreased (6.9 ± 1.4) vs (9.1 ± 2.1) d, t = 17.48, P <0.01]. No adverse reactions occurred. Conclusion Neonatal pneumonia antibiotic-associated diarrhea supplemented with probiotics can effectively reduce the incidence of antibiotic-associated diarrhea, reduce the degree of diarrhea and reduce hospital stay.