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目的:研究探讨年龄、性别因素与胃癌的发病和临床病理学之间的关系。方法:收集1993年1月至2000年12月在本院接受外科手术治疗的1554例胃癌患者的术后病理学资料,比较分析不同性别、年龄段胃癌患者的分布状况及临床病理学差异。结果:胃癌的发病率男女均随年龄增长而升高,51～70岁为高峰年龄段(49%～61%);40岁以下女性发病多于男性,40岁以上则相反。40岁以下男女胃癌患者的组织学类型大多为分化较差的低、未分化腺癌或印戒细胞癌(85%～93%),40岁以上患者中中分化腺癌的比例逐渐增高,尤以男性明显;低分化腺癌和印戒细胞癌是各年龄段女性胃癌的主要组织学类型(61%～89%)。不同性别、年龄段胃癌患者的淋巴结转移状况相同。结论:不同性别、年龄段胃癌患者具有不同的发病状况和组织学类型,提示可能存在不同的发病机制和预后。
Objective: To investigate the relationship between age, gender and the incidence of gastric cancer and clinicopathology. Methods: The postoperative pathological data of 1554 cases of gastric cancer who underwent surgery in our hospital from January 1993 to December 2000 were collected to analyze the distribution and clinicopathological difference of gastric cancer patients of different genders and ages. Results: The incidence of gastric cancer in both men and women increased with age, 51 to 70 years of age for the peak age (49% to 61%); women under 40 years of age more than men, 40 years of age is the opposite. The histological types of gastric cancer patients under 40 years of age are mostly poorly differentiated low, undifferentiated adenocarcinoma or signet ring cell carcinoma (85% ~ 93%), 40 patients over the age of the proportion of moderately differentiated adenocarcinoma gradually increased, especially Obviously male; poorly differentiated adenocarcinoma and signet-ring cell carcinoma of all ages is the main histological type of gastric cancer (61% to 89%). Lymphatic metastasis of gastric cancer patients of different genders and ages is the same. CONCLUSION: Patients with different genders and ages have different morbidity and histological types, indicating that there may be different pathogenesis and prognosis.