报道了一种基于聚乙烯醇缩丁醛(PVB)和金溶胶,把乙型肝炎表面抗体(HBsAb)固定在铂金电极上,用来检测乙型肝炎表面抗原(HBsAg)的一种新型电位型免疫传感器.该传感器制作简单、响应时间较短(<3min)、具有良好的选择性和灵敏度,线性范围是4 4μg/L～240μg/L,检出限(3σ)为1 4μg/L.将该电极用于临床上对乙型肝炎表面抗原的检测,与酶联免疫法相比,符合率为91 3%. Reported a novel potentiometric method for the detection of hepatitis B surface antigen (HBsAg) based on the immobilization of hepatitis B surface antigen (HBsAb) on platinum electrodes based on polyvinyl butyral (PVB) and gold sol The sensor has the advantages of simple preparation, short response time (<3min), good selectivity and sensitivity, linear range 4 4μg / L ~ 240μg / L and limit of detection 3 4μg / L. The electrode for the clinical detection of hepatitis B surface antigen, compared with enzyme-linked immunosorbent assay, the coincidence rate was 91 3%.