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该项研究用3mKCl提取胃癌抗原（GCaAg），免疫小鼠制备特异性转移因子（STF），应用巨噬细胞（MΦ）移动抑制试验（MIT），测得GCaAg致敏动物淋巴细胞加GCaAg和加STF＋GCaAg试验组，MΦ移动面积明显小于对照组（P＜0．001和P＜0．01）。移动指数（MI）在0．8以下，均为阳性。在MTT比色中加GCaAg和加STF组OD值明显大于空白对照组（P＜0．05和P＜0．001）；淋转指数STF组最高（1．73）。两项试验提示STF确有激活淋巴细胞的作用，并显示抗原依赖的特异性活性。在MIT中显示STF作用无种属特异性限制。这一点为动物来源的STF治疗人类肿瘤提供了依据。
In this study, gastric cancer antigen (GCaAg) was extracted with 3mKCl, specific transfer factor (STF) was prepared in immunized mice, macrophages (MΦ) migration inhibition test (MIT) was used, and GCaAg-sensitized animal lymphocytes plus GCaAg were measured. In the STF+GCaAg test group, the moving area of MΦ was significantly smaller than that of the control group (P<0.001 and P<0.01). The mobile index (MI) was less than 0.8 and all were positive. The OD values of GCaAg and STF groups in the MTT colorimetric group were significantly higher than those in the blank control group (P<0.05 and P<0.001); the highest in the dialyzed index STF group (1.73). Two trials suggest that STF does activate lymphocytes and show antigen-specific activity. There was no species-specific limitation of STF action at MIT. This provides a basis for animal-derived STFs to treat human tumors.