目的探讨幽门螺杆菌(Hp)与消化性溃疡的关系。方法选取80例消化性溃疡患者为研究对象,给予患者胃镜检查,并行活体组织、快速尿素酶及Hp感染检查。结果 80例患者中,胃溃疡25例,十二指肠溃疡48例,复合性溃疡7例;34例Hp呈阳性,其中胃溃疡10例,十二指肠溃疡20例,复合性溃疡4例;46例Hp呈阴性,其中胃溃疡15例,十二指肠溃疡28例,复合性溃疡3例。结论 Hp感染是导致消化性溃疡的重要病因,应尽早进行检查治疗。 Objective To investigate the relationship between Helicobacter pylori (Hp) and peptic ulcer. Methods Eighty patients with peptic ulcer were enrolled in this study. The patients underwent endoscopy, parallel biopsy, rapid urease and Hp infection. Results Among the 80 patients, there were 25 cases of gastric ulcer, 48 cases of duodenal ulcer and 7 cases of complex ulcer; 34 cases were positive for Hp, including 10 cases of gastric ulcer, 20 cases of duodenal ulcer and 4 cases of complex ulcer ; 46 cases of Hp negative, including 15 cases of gastric ulcer, duodenal ulcer in 28 cases, 3 cases of complex ulcer. Conclusion Hp infection is an important cause of peptic ulcer disease and should be examined and treated as soon as possible.