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本文报告８２例大肠癌随机分为两组：试验组４５例，除施行根治术外。辅加肠腔５－ＦＵ化疗和术后第１、２天５－ＦＵ全身化疗；对照组３７例，单纯施行根治术。Ｄｕｋｅｓ’Ｃ期病人试验组３年、５年和８年生存率分别为７５．５％、６５．４％、和２８．５％，而对照组仅５８．３％、２５．０％和５．６％，两者差异有显著性（Ｐ＜０．０５）。另外，试验组肝转移比对照组少。故此法是提高结、直肠癌根治术疗效和防止肝转移的重要措施，值得推广应用。
This article reports 82 cases of colorectal cancer were randomly divided into two groups: the experimental group of 45 cases, in addition to the implementation of radical surgery. Supplemented with 5-FU chemotherapy in the intestine and 5-FU systemic chemotherapy on the 1st and 2nd days after surgery; 37 cases in the control group were treated with radical surgery. The 3-year, 5-year, and 8-year survival rates for the Dukes’ C phase patient trial group were 75.5%, 65.4%, and 28.5%, respectively, compared with 58.3%, 25.0%, and 5 for the control group. The difference between the two groups was statistically significant (P<0.05). In addition, the experimental group had less liver metastases than the control group. Therefore, this method is an important measure to improve the curative effect of radical resection of rectal cancer and prevent liver metastasis, and it is worthy of popularization and application.