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目的探讨a-1b干扰素(赛若金)穴位注射治疗老年慢性乙型肝炎疗效。方法随机选择67例老年慢性乙型肝炎患者,其中治疗组38例,采用a-1b干扰素10μg行双侧足三里穴位注射;对照组29例,采用α-1b干扰素30μg肌内注射;两组疗程均6个月。结果治疗组HBeAg和HBVDNA的阴转率高于对照组,(P值均<0.05)。结论提示小剂量α-1b干扰素对老年慢性乙肝病毒感染有一定抑制和清除作用,采用足三里穴位注射者,疗效优于肌内注射者。
Objective To investigate the therapeutic effect of a-1b interferon (SAFR) acupoint injection on senile chronic hepatitis B (CHB). Methods A total of 67 elderly patients with chronic hepatitis B were randomly selected, including 38 in the treatment group and 10 μg of a-1b interferon injections on both sides of the Zusanli acupoint. In the control group, 29 cases were injected intramuscularly with α-1b interferon (30μg) Group therapy were 6 months. Results The negative conversion rate of HBeAg and HBVDNA in the treatment group was higher than that in the control group (P <0.05). Conclusions Low-dose interferon α-1b has certain inhibitory and eradication effects on elderly chronic hepatitis B virus infection. The injection of Zusanli points is superior to intramuscular injection.