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硝苯吡啶又称心痛定,临床上主要用于治疗各型心绞痛和高血压。随着广泛应用,其不良反应发生率达17～40％。作者对该药副作用综述如下:(1)心血管系统:硝苯吡啶能扩张周围血管,降低血压,个别病人可出现反射性心动过速。有报道4例服用硝苯吡啶后30分钟引起心绞痛者。该药有时不仅不能缓解心绞痛,反而使之加重。也有报道口服该药大于80毫克/日时,可导致某些顽固性心绞痛病人发生低血压、心绞痛和可逆性心肌缺血。与β-阻滞剂或硝酸酯类合用时,尤须注意。另外少数心衰患者服用该药20毫克或30毫克后,可出现低血压或肺水肿。有资
Nifedipine, also known as nifedipine, clinically used for the treatment of various types of angina pectoris and hypertension. With the widespread application, the incidence of adverse reactions reached 17 to 40%. The authors summarized the side effects of the drug are as follows: (1) Cardiovascular system: Nifedipine can expand peripheral blood vessels, lower blood pressure, individual patients may have reflex tachycardia. 4 cases of nifedipine have been reported 30 minutes after taking angina caused. The drug sometimes not only can not relieve angina, but to make it worse. It has also been reported oral administration of the drug is greater than 80 mg / day, can lead to some patients with refractory angina hypotension, angina and reversible myocardial ischemia. Especially with β-blockers or nitrates when combined. In addition, a small number of heart failure patients taking the drug 20 mg or 30 mg, there may be hypotension or pulmonary edema. Funded