目的　探讨经腹部、阴道二维超声及彩色多普勒鉴别良、恶性卵巢肿瘤的特点及意义。方法　自2 0 0 0年 1月至 2 0 0 2年 1月 ,对 2 5 0例卵巢肿瘤进行二维超声及彩色多普勒检测 ,并对良恶性卵巢肿瘤的形态、包膜、腹水、周边、内部血流阻力指数及血清CA12 5进行比较。结果　良恶性卵巢肿瘤的形态、包膜差异有显著性(P <0 0 1)。 6 4 %的恶性肿瘤可测出腹水 ,而良性肿瘤腹水仅占 0 7%。两者周边血流差异无显著性 ( P >0 0 5 ) ,内部血流差异有显著性 (P <0 0 1) ;17例中晚期恶性卵巢肿瘤病人的血清CA12 5均增高。结论　超声形态学和彩色多普勒探查卵巢肿瘤的动脉血流阻力指数 ,辅助血清CA12 5测值 ,是鉴别良恶性卵巢肿瘤的有效方法 Objective To investigate the characteristics and significance of transabdominal and vaginal two-dimensional ultrasonography and color Doppler in differentiating benign and malignant ovarian tumors. Methods From January 2000 to January 2002, 250 cases of ovarian tumors were examined by two-dimensional sonography and color Doppler. The morphological, Peripheral, internal flow resistance index and serum CA12 5 were compared. Results There was a significant difference in morphology and capsule between benign and malignant ovarian tumors (P <0.01). Ascites was detectable in 4 of 4% of malignancies, while ascites in benign tumors accounted for only 0 7%. There was no significant difference in the peripheral blood flow between the two groups (P> 0.05), and the difference of internal blood flow was significant (P <0.01). Serum CA12 5 levels were higher in 17 patients with advanced malignant ovarian tumors. Conclusion Ultrasound morphology and color Doppler detection of ovarian tumor arterial resistance index, auxiliary serum CA12 5 measurement is an effective method to identify benign and malignant ovarian tumors