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70年前人们就认识到一种由鼻息肉、鼻窦炎、哮喘和阿斯匹林特应质组成的综合征,它不同于鼻息肉或哮喘的变态反应类型。此综合征多见于成年人,有吸入过敏史,服阿斯匹林后出现呼吸道阻塞症状,对乙酰胆碱及组胺敏感,对类固醇有依赖性。其真正的病因尚不明了。作者从12名患者的鼻息肉和窦腔组织中采取近700份标本,进行了组织病理学和免疫球蛋白检查。其中男女各半,年龄27～53岁,均经临床诊治和实验室全面检查,全部接受过鼻息肉和鼻窦手术。
It was 70 years ago that people recognized a syndrome consisting of nasal polyps, sinusitis, asthma and aspirin, which is different from the type of allergy to nasal polyps or asthma. This syndrome is more common in adults, allergic history of inhalation, respiratory symptoms of obstruction after taking aspirin, sensitive to acetylcholine and histamine, steroid dependent. The real cause is unknown. The authors took nearly 700 specimens of nasal polyps and sinus tissue from 12 patients for histopathology and immunoglobulin tests. Half of them men and women, aged 27 to 53 years old, all by clinical diagnosis and laboratory tests, all received nasal polyps and sinus surgery.