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microRNA(miRNA)功能异常在肿瘤发生发展中具有极其重要的作用。笔者就miRNA的合成与功能,以及miRNA功能异常在肿瘤细胞的周期、凋亡和浸润转移等恶性表型中的作用进行综述,以探讨其在肿瘤早期诊断与复发监测中的意义。
MicroRNA (miRNA) dysfunction in tumor development has an extremely important role. The author reviewed the roles of miRNA synthesis and function, and miRNA dysfunction in malignant phenotypes such as cycle, apoptosis and invasion and metastasis of tumor cells to explore its significance in the early diagnosis and recurrence of tumors.