用晚孕兔肝受体建立血清人生长激素(hGH)的放射受体测定法(RRA),本法灵敏度为90±11 pg/管,特异性高,仅与人泌乳素有2.4％的交叉反应,准确性好,肢端肥大症病人血清的稀释曲线与标准曲线完全平行,重复性较好,批内和批间变异分别为11.3～13.3％和7.7～18.8％。64例正常成人空腹血清RRA hGH水平平均为1.2±0.3 ng/ml(M±SE),其中57例hGH水平<1ng/ml. 23份活动性肢端肥大症病人血清hGH平均为98.7±33.7 ng/ml,明显高于正常人.证实RRA hGH能较好地反映hGH分泌功能. Radioreceptor assay (RRA) of serum human growth hormone (hGH) was established using late pregnant rabbit liver receptors with sensitivity of 90 ± 11 pg / tube and specificity of only 2.4% with human prolactin The results showed that the dilution curves of patients with acromegaly were completely parallel to the standard curve and had good reproducibility. The intra-and inter-assay variation was 11.3-13.3% and 7.7-18.8% respectively. The average level of RGR hGH in 64 normal adults was 1.2 ± 0.3 ng / ml (M ± SE), of which 57 cases had hGH level <1 ng / ml. The average serum hGH level in 23 active acromegaly patients was 98.7 ± 33.7 ng / ml, significantly higher than normal, confirmed that hRH hGH can better reflect the secretory function of hGH.