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利用糖皮质激素的抗炎和免疫抑制作用可治疗多种口腔粘膜病。这些疾病均以继发于对自体组织的超敏反应的炎症为特征。糖皮质激素对它们的原发机制无作用,但能干扰其炎症反应和T、B 细胞的功能。所以,可用类固醇来缓解疾病急性期或长期抑制宿主全身反应。糖皮质激素的抗炎作用超生理浓度的皮质激素有抗炎作用,这是因为它有稳定所有生物膜的能力。它能稳定内皮细胞膜,使血管扩张和渗透性减少,从而减少水肿形成、纤维蛋白沉积;白细胞
The use of glucocorticoid anti-inflammatory and immunosuppressive effects can treat a variety of oral mucosal disease. These diseases are all characterized by inflammation secondary to hypersensitivity to autologous tissue. Glucocorticoids have no effect on their primary mechanism, but interfere with their inflammatory response and T, B cell function. Therefore, steroids can be used to alleviate the disease acute or chronic host inhibition of systemic reactions. Anti-inflammatory effects of glucocorticoids Super-physiological concentrations of corticosteroids have an anti-inflammatory effect because of their ability to stabilize all biofilms. It stabilizes the endothelial cell membrane and reduces vasodilation and permeability, thereby reducing the formation of edema and fibrin deposition. Leukocytes