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目的探讨依那普利治疗老年肾性高血压时对左室结构和功能的影响。方法观察２１例老年肾性高血压患者应用依那普利治疗前后左室结构及功能改变。结果治疗后血压较治疗前明显降低。用药后室间隔、左室后壁及左室重量指数均有不同程度下降（Ｐ＜０．０５），Ａ峰速度及Ａ／Ｅ比值明显下降，Ｅ峰速度明显增高（Ｐ＜０．０５）。结论依那普利治疗老年肾性高血压有效降压的同时亦可逆转左室肥厚，改善左室舒张功能。
Objective To investigate the effect of enalapril on left ventricular structure and function in elderly patients with renal hypertension. Methods The changes of left ventricular structure and function were observed in 21 elderly patients with renal hypertension before and after enalapril treatment. Results After treatment, blood pressure was significantly lower than before treatment. After treatment, the interventricular septum, left ventricular posterior wall and left ventricular mass index decreased to different extents (P <0.05), A peak velocity and A / E ratio decreased significantly, and E peak velocity increased significantly (P <0.05) . Conclusions Enalapril can effectively depress the left ventricular hypertrophy and improve left ventricular diastolic function in elderly patients with hypertension.