随着受体研究的不断深入,发现性质不同的受体亚型越来越多。应用多种受体法对样品尤其是原有的大量化合物库进行系统的筛选,是发现具有特异生物活性作用新药的重要途径。本文对这种受体筛选法在基本原理、测定技术过程、活性标准、影响因素以及计算机程序化等方面进行了论述。 With the deepening of receptor research, more and more receptor subtypes have been discovered with different properties. The systematic screening of samples, especially the original large number of compound libraries, using a variety of receptor methods is an important way to find new drugs with specific biological activity. In this paper, the receptor screening method in the basic principles, determination of technical process, activity standards, influencing factors, and computer programs and so on are discussed.