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引言小蘖硷(Berberine)在很多文献中亦有译作黄连素,黄连硷(易与Coptisine混淆),及黄柏素等名称。根据近代在微生物学上的研究[1——6],认为小蘖硷在体外实验有抑制或杀死:伤寒桿菌,副伤寒桿菌,金黄色葡萄状球菌,链球菌,霍乱弧菌,異型痢疾桿菌,大肠桿菌及结核桿菌等的作用。它的硫酸盐及盐酸,并为别被收载在B.P.C.(1949)及药品规范(1956)中。盐酸小蘖硷的各种制剂应用更广,特别如盐酸黄连硷片(药品规范及制剂规范中均收载),盐酸小蘖硷栓剂(治妇女阴道滴虫,宫颈炎等),盐酸黄连素滴眼液等尤被欢迎。小蘖硷过去多从黄连中提取,但是若从黄柏中去提制盐酸小蘖硷,不但原料不感缺乏,而且成本要比
Introduction Berberine has also been translated into berberine, Huang Lianxi (easily confused with Coptisine), and Huang Baisu. According to the recent microbiological studies [1–6], it was considered that the indole was inhibited or killed in vitro: Salmonella typhi, Paratyphoid bacillus, Staphylococcus aureus, Streptococcus, Vibrio cholera, dysentery The role of Bacillus, E. coli and Mycobacterium tuberculosis. Its sulfate and hydrochloric acid are not included in B.P.C. (1949) and Drug Specification (1956). Various preparations of chlorhexidine hydrochloride are more widely used, such as chlorpyrifos hydrochloride tablets (recognized in drug specifications and preparation specifications), chlorhexidine hydrochloride suppositories (treasion of vaginal trichomoniasis, cervicitis, etc.), and berberine hydrochloride. Eye drops, etc. are particularly welcome. In the past, Xiaolong had been extracted from Coptis chinensis, but if it was extracted from Phellodendron chinense, it was not only lacking in raw materials, but also cost