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近来阿司匹林和氯吡格雷抵抗受到了越来越多的关注,它被用来描述冠状动脉疾病患者在用阿司匹林和氯吡格雷抗血小板治疗后仍发生不良心血管事件。明确抵抗的原因和机制将使冠状动脉疾病患者受益匪浅。现就阿司匹林和氯吡格雷抵抗的定义、可能机制和检测方法做一综述。
Aspirin and clopidogrel resistance have gained more and more attention lately and are used to describe adverse cardiovascular events in patients with coronary artery disease after antiplatelet therapy with aspirin and clopidogrel. Clearly the causes and mechanisms of resistance will benefit patients with coronary artery disease. Now the definition of aspirin and clopidogrel resistance, possible mechanisms and detection methods to do a review.