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除了母体基因和环境影响因素,胎儿印记基因的变化也可影响怀孕期间的母亲血压。该研究的目的是测试在2个已建立的出生队列(剑桥婴儿生长和健康研究)中1160个DNA三联体的16个印迹基因的多态性与母体平均动脉压之间的关系,并试图验证在1367例高血糖和不良妊娠结局研究受试者中是否存在同样的关系。结果:独立于胎儿性别的单因素分析
In addition to maternal genes and environmental factors, changes in fetal imprinting genes can also affect maternal blood pressure during pregnancy. The aim of this study was to test the relationship between the polymorphism of 16 imprinted genes of 1160 DNA triplets and maternal mean arterial pressure in two established birth cohorts (Cambridge Infant Growth and Health Study) and to try to verify The same relationship exists in 1367 subjects with hyperglycemia and adverse pregnancy outcomes. Results: Univariate analysis independent of fetal sex