为探讨５ＨＴ２受体与心肌缺血再灌注损伤的关系，观察５ＨＴ２受体阻断剂ｋｅｎｔａｎｓｅｒｉｎ对心肌缺血再灌注大鼠室颤及左室内压＋ｄｐ／ｄｔｍａｘ及－ｄｐ／ｄｔｍａｘ的影响。结果表明，ｋｅｎｔａｎｓｅｒｉｎ可拮抗缺血性心功能障碍和再灌室颤。提示５ＨＴ２受体参与了缺血性心功能障碍和再灌室性心律失常的发生。 To investigate the relationship between 5HT2 receptor and myocardial ischemia  reperfusion injury and observe the effect of 5HT2 receptor antagonist kentanserin on ventricular fibrillation and left ventricular pressure + dp / dtmax and -dp / dtmax impact. The results show that, kentanserin can antagonize ischemic heart failure and reperfusion ventricular fibrillation. Tip 5  HT2 receptors involved in ischemic heart failure and reperfusion ventricular arrhythmias.