论文部分内容阅读
目的:探讨区域淋巴结转移与食管鳞状细胞癌预后两者间的关系。方法:以Meta分析软件综合分析国内外1980-2009年关于pN0期食管鳞状细胞癌区域淋巴结微转移与预后关系的文献。结果:总计4篇文献符合要求被纳入分析,累计病例188例。常规病检阴性淋巴结微转移的检测率为1.36%～2.43%,阳性病例的比例达36.6%～66.1%。pN0期食管鳞状细胞癌淋巴结微转移患者与非微转移患者的3、5年总生存率比较,其合并ORs值分别为2.37(95%CI=1.17～4.78,P<0.05)和3.66(95%CI=1.85～7.24,P<0.01)。结论:区域淋巴结微转移是影响pN0期食管鳞状细胞癌患者术后生存率的重要因素。中华肿瘤防治杂志,2011,18(20):1616-1619
Objective: To investigate the relationship between regional lymph node metastasis and prognosis of esophageal squamous cell carcinoma. Methods: Meta analysis software was used to analyze the literature about the relationship between micrometastasis and prognosis of pN0 esophageal squamous cell carcinoma in the world from 1980 to 2009. Results: A total of 4 articles were included in the analysis, with a total of 188 cases. The detection rate of routine disease-negative lymph node micrometastases was 1.36% ~ 2.43%, and the positive rate was 36.6% ~ 66.1%. The combined ORs of the 3-year and 5-year overall survival rates of patients with pN0 esophageal squamous cell carcinoma with lymph node micrometastasis and non-micrometastasis were 2.37 (95% CI = 1.17-4.78, P <0.05) and 3.66 % CI = 1.85 ~ 7.24, P <0.01). Conclusion: The regional lymph node micrometastasis is an important factor affecting the postoperative survival rate of pN0 esophageal squamous cell carcinoma patients. Chinese Journal of Cancer Prevention and Treatment, 2011,18 (20): 1616-1619