目前常用的血清肿瘤标志物，如 ＣＡ１９－９、 ＣＡ５０及癌胚抗原（ＣＥＡ）等的检测对早期诊断胰腺癌价值不大。通过内镜逆行胰胆管造影（ＥＲＣＰ）插管至胰管吸取胰液来检测肿瘤标志物，可明显提高胰腺癌的早期诊断率，特别是对小胰腺癌。本文就近年胰液中肿瘤标志物检测 Currently used serum tumor markers, such as CA19-9, CA50 and carcinoembryonic antigen (CEA) and other detection of early diagnosis of pancreatic cancer is of little value. Detection of tumor markers by endoscopic retrograde cholangiopancreatography (ERCP) intubation to the pancreatic duct for pancreatic juice uptake can significantly improve the early diagnosis of pancreatic cancer, especially for small pancreatic cancer. In this paper, the detection of tumor markers in pancreatic juice in recent years