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目的:探讨DOT管理模式在肺结核疾病控制中的应用。方法:对2010~2012年在浙江省上虞市人民医院结核病门诊接受治疗的460例肺结核患者进行跟踪调查,将其随机分成观察组和对照组,每组230例。观察组采取DOT管理模式下用化疗药物治疗,其中初治115例,复治115例;对照组直接采取化疗药物治疗,初治115例,复治115例。之后比较两组初治疗的临床治愈率、复治疗的临床治愈率和总治愈率。结果:观察组初、复治疗的治愈率分别为96.52%和90.43%,对照组初、复治疗的治愈率分别为88.70%和82.61%,观察组的初、复治疗的治愈率明显高于对照组;观察组总治愈率为93.48%,对照组总治愈率为85.66%,观察组总治愈率明显高于对照组。结论:采取DOT管理模式下的化疗药物治疗肺结核比直接采取化疗药物治疗肺结核治愈率高,并可提高结核病防治效果。
Objective: To explore the application of DOT management in the control of pulmonary tuberculosis. Methods: A total of 460 pulmonary tuberculosis patients treated in the tuberculosis clinic of Shangyu People ’s Hospital of Zhejiang Province from 2010 to 2012 were randomly divided into observation group and control group, with 230 cases in each group. The observation group was treated with chemotherapy drugs under the DOT management mode, of which 115 cases were newly diagnosed and 115 cases were retreated. In the control group, 115 cases were treated with chemotherapy alone, and 115 cases were treated initially. After comparing the two groups of initial treatment clinical cure rate, clinical cure rate and total cure rate. Results: The cure rates of primary and secondary treatment in observation group were 96.52% and 90.43% respectively. The cure rates of primary and secondary treatment in control group were 88.70% and 82.61% respectively. The cure rate of primary and secondary treatment in observation group was significantly higher than that of control group Group. The total cure rate was 93.48% in the observation group and 85.66% in the control group. The total cure rate in the observation group was significantly higher than that in the control group. Conclusion: The treatment rate of tuberculosis treated with chemotherapeutic drugs under DOT management mode is higher than that of chemotherapy drugs directly administered, and the tuberculosis control effect can be improved.