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本文对5例附睾腺瘤样瘤的组织学和免疫组化特征进行了观察。结果表明,肿瘤对细胞角蛋白(cytokeratin)、上皮膜抗原(EMA)和波形蛋白(vementin)均呈阳性反应,对第八因子相关抗原(FvlllRAg)均呈阴性表达。这些结果明确揭示了肿瘤细胞的双向分化特征,进一步支持该瘤间皮起源的观点。在病理诊断中,该瘤须与上皮样血管瘤和腺癌进行鉴别。
In this paper, 5 cases of epididymis adenoma tumor histological and immunohistochemical characteristics were observed. The results showed that the tumors showed positive reaction to cytokeratin, EMA and vementin, and negative to FvlllRAg. These results clearly reveal the bi-directional differentiation of tumor cells and further support the idea of the origin of this mesothelium. In the pathological diagnosis, the tumor must be differentiated from epithelioid hemangiomas and adenocarcinomas.