1979～1980年Kung 等利用杂交瘤技术研制出一系列鼠抗人胸腺细胞和T 细胞表面抗原的单克隆抗体(OKT 系统)。以后Good 的实验室也研制出Leu 系统单克隆抗体。这些单克隆抗体的出现为临床判断患者的免疫调节状况以及器官移植病人的免疫监护提供了简便快速的途径。利用单克隆抗体 From 1979 to 1980 Kung et al. Developed a series of monoclonal antibodies (OKT system) against mouse thymocytes and T cell surface antigens using the hybridoma technique. After Good’s laboratory also developed Leu system monoclonal antibody. The emergence of these monoclonal antibodies provides a quick and easy way to clinically determine the patient’s immunomodulatory status and immune monitoring of organ transplant patients. Use of monoclonal antibodies