内源性库兴氏综合征的病因一般可分为三种:(1)库兴氏病,通常为垂体腺瘤分泌ACTH过多,(2)异位ACTH综合征,通常为良性或恶性肿瘤分泌ACTH所致,(3)良性或恶性肾上腺皮质肿瘤自主性分泌过多的皮质醇及其它皮质激素。传统的鉴别方法有赖于测定大剂量(8mg/日)地塞米松试验后的24小时尿皮质醇或其它糖皮质激 The etiology of endogenous Cushing’s syndrome can generally be divided into three types: (1) Cushing’s disease, usually ACTH secretion from pituitary adenomas, (2) ectopic ACTH syndrome, usually benign or malignant Secretion of ACTH caused by (3) benign or malignant adrenal tumors autonomously excessive secretion of cortisol and other corticosteroids. The traditional method of identification relies on the determination of urinary cortisol or other glucocorticoids 24 hours after a high dose (8 mg / day) dexamethasone test