结核样型麻风的上皮样细胞反应和瘤型麻风有泡沫细胞形成,一直被认为是麻风病理上特异性的改变。近年来通过对动物感染模型的研究,以及对麻风患者神经病变,包括日常外检工作中常见的真皮神经病变,进行了大量的光学及电子显微镜观察,对麻风神经病变有了较为充分的认识,下面就各型麻风的神经病变作简要的叙述。神经感染的早期麻风杆菌进入人体的途径至今尚未查明,但已知杆菌进入机体后,最初免疫系统不能察觉,它不受阻碍地散布全身。杆菌有很强的进入外周神经内膜的能力,但原因不明。感染的最初期,杆菌存在于神经干和真皮神经的雪旺氏细胞内,电镜显示雪旺氏细 Epithelial-like cell responses to tuberculous leprosy and the formation of foam cells in leprous leprosy have long been considered pathologically specific changes in leprosy. In recent years, a large number of optical and electron microscopic observations have been made on the animal model of infection and on the neuropathy of leprosy patients, including the dermal neuropathy common in the daily routine examination. The leprosy neuropathy has a more adequate understanding, The following brief description of the various types of leprosy neuropathy. The pathways into the body of early-stage leprosy that have been infected by the nervous system have not yet been identified, but it is known that once the bacillus enters the body, the immune system initially can not detect it and spreads its body unhindered. Bacilli have a strong ability to enter the peripheral nerves, but the cause is unknown. The initial infection, Bacillus present in the neural stem and dermal nerve Schwann cells, electron microscopy showed Schwann’s fine