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目的:探讨分析人粒细胞集落刺激因子对于化疗后白细胞减少的预防效果。方法:选取100例恶性肿瘤患者分为二组,观察组在化疗前皮下注射给予使用rh G-CSF,对照组则不使用,观察两组患者化疗后白细胞减少状况。结果:观察组患者粒细胞减少发生率及发生程度均明显低于对照组(P<0.05)。结论:化疗前使用人粒细胞集落刺激因子可显著改善化疗后的白细胞减少状况,提高患者生命质量。
Objective: To investigate the preventive effect of human granulocyte-colony stimulating factor on leukopenia after chemotherapy. Methods: One hundred patients with malignant tumor were divided into two groups. The observation group was given rhG-CSF subcutaneously before chemotherapy and the control group was not used. The leukopenia after chemotherapy was observed in both groups. Results: The incidence and occurrence of granulocytopenia in the observation group were significantly lower than those in the control group (P <0.05). Conclusion: The use of human granulocyte colony-stimulating factor before chemotherapy can significantly improve the leukopenia after chemotherapy and improve the quality of life of patients.