论文部分内容阅读
灵长类动物脑组织移植报道较少,而且局限于胎脑黑质组织移植治疗帕金森病。 本研究参考Willis移植技术及Cotman脑皮质延迟移植技术,将同种猴胎脑组织移植到成年猴的大脑皮质下,并应用组织学及行为学观察方法研究了猴胎脑移植的存活情况。 材料和方法 1.动物:健康成年太行山猕猴10只(雌性4只,雄性6只),年龄5～8岁,体重3～7kg,其中孕猴2只,妊娠10～12周。
Primate brain tissue transplantation less reported, and limited to fetal brain substantia nigra tissue transplantation for the treatment of Parkinson’s disease. In this study, Willis transplantation and Cotman cortical delayed graft technique were used in this study. The same type of monkey fetal brain tissue was transplanted into the cerebral cortex of adult monkeys. The survival of the fetal fetal brain was studied by histological and behavioral methods. MATERIALS AND METHODS 1. Animals: 10 healthy Taihangshan macaques (4 females and 6 males) aged 5 to 8 years and weighing 3 to 7 kg, including 2 pregnant males and 10 to 12 weeks of gestation.