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目的:探讨替米沙坦治疗老年轻、中度高血压患者的疗效和安全性。方法:选取80例年龄≥60岁的轻、中度高血压患者,将其随机平均分为观察组和对照组,每组40例。观察组给予替米沙坦治疗,对照组给予氯沙坦治疗,两组均连续用药两个月,比较两组的治疗效果及不良反应。结果:观察组总有效率是90%,对照组总有效率是62.5%,观察组明显高于对照组,差异具有统计学意义(P<0.05);观察组不良反应发生率是10%,对照组是12.5%,两组不存在统计学差异(P>0.05)。结论:应用替米沙坦治疗轻、中度高血压的老年患者,有效性及安全性高,值得临床进一步推广应用。
Objective: To investigate the efficacy and safety of telmisartan in the treatment of elderly patients with moderate and severe hypertension. Methods: Eighty 80 mild and moderate hypertensive patients aged 60 years or older were randomly divided into observation group and control group, 40 cases in each group. The observation group was treated with telmisartan and the control group with losartan. The two groups were treated continuously for two months. The treatment effect and adverse reactions were compared between the two groups. Results: The total effective rate was 90% in the observation group and 62.5% in the control group. The observation group was significantly higher than the control group (P <0.05). The incidence of adverse reactions in the observation group was 10% Group was 12.5%, there was no statistical difference between the two groups (P> 0.05). Conclusion: Telmisartan in elderly patients with mild to moderate hypertension has high efficacy and safety, which is worth further clinical application.