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目的 了解呼吸机相关性肺炎 ( VAP)的危险因素、病原菌种类、治疗及预后。方法 对我院 30例 VAP患者进行回顾性调查分析。结果 原发病以急性重症胰腺炎居多。VAP发生前已有其他部位感染者占 33.3% ,已有损伤和 /或手术者占 4 6.6%。VAP发生前 76.7%的病例使用了制酸剂 ,10 0 %的病例使用了抗菌药物。VAP病原菌中 G-杆菌占 84 .2 % ,铜绿假单胞菌占 G-杆菌的 50 %。选用频率较高的三种抗菌药物是三代头孢菌素、伊米配能、青霉素类。该组病例死亡率为 33.3%。结论 重症感染、使用抗菌药物和制酸剂、手术和损伤是 VAP发生的易感因素。VAP病原菌主要为 G-杆菌 ,尤以铜绿假单胞菌为多
Objective To understand the risk factors, pathogens, treatment and prognosis of ventilator-associated pneumonia (VAP). Methods 30 cases of VAP in our hospital were retrospectively analyzed. The results of primary disease with acute severe pancreatitis mostly. 33.3% of the patients had other parts of the VAP before the occurrence of VAP, and 46.6% of the patients had injuries and / or surgery. Antacids were used in 76.7% of cases before VAP and antacids in 100% of cases. G-bacilli accounted for 84.2% in VAP pathogens and Pseudomonas aeruginosa accounted for 50% of G-bacteria. Three high frequency of selection of antimicrobial drugs is the third generation cephalosporins, imipenem, penicillins. The case fatality rate was 33.3%. Conclusions Severe infection, use of antimicrobial agents and antacids, surgery and injury are the predisposing factors for VAP. VAP pathogens are mainly G-bacteria, especially Pseudomonas aeruginosa