脑利钠肽和肾功能被认为是充血性心力衰竭的预后因子,但二者之间的相互关系并无仔细研究。日本学者Tsutamoto 及其同事的研究发现,肾小球滤过率下降部分导致了充血性心力衰竭的患者脑利钠肽水平升高,这一研究结果刊登在Jour— bak of the American College of Cardi- ology杂志上。研究者测量了366例充血性心衰患者主动脉弓和冠脉窦的脑利钠肽水平,肾功能则以Cockcroft—Gault公式计算所得的肾小球滤过率来表示。研究发现左室射 Brain natriuretic peptide and renal function are considered prognostic factors of congestive heart failure, but the relationship between the two has not been carefully studied. A study by Japanese scholar Tsutamoto and colleagues found that a decrease in glomerular filtration rate in part caused an increase in brain natriuretic peptide in patients with congestive heart failure, a finding published in Jour- bak of the American College of Cardi- ology magazine. The researchers measured brain natriuretic peptide levels in the aortic arch and coronary sinus in 366 patients with congestive heart failure. Renal function was calculated using the calculated glomerular filtration rate from the Cockcroft-Gault formula. Study found that left ventricular injection