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多囊卵巢综合征(PCOS)由于妇女表现有慢性的黄体生成素(LH)脉冲频率和幅度的增高,促性腺激素释放激素(GnRH)释放可能已达最高限度;因而,枸橼酸克罗米芬(CC)治疗似乎不能进一步增加PCOS患者LH的释放频率。作者通过对17名PCOS妇女和9名正常妇女的观察验证了前述假设。
Polycystic ovary syndrome (PCOS) The release of gonadotropin-releasing hormone (GnRH) may have reached its maximum due to the increased frequency and amplitude of chronic LH events in women; thus, clomiphene citrate ( CC) did not appear to further increase the frequency of LH release in patients with PCOS. The authors validated the aforementioned hypothesis by observing 17 PCOS women and 9 normal women.