作者应用双盲法探讨静注甘油对急性卒中后有轻偏瘫发作的老年病人的疗效。 173例急性脑梗塞病人在症状发作后48小时内进入研究,患者均有轻偏瘫存在,但无可能的脑干卒中,一过性局部缺血、以往猝中后遗症、其他主要的神经学混乱和现时的心肌梗塞、糖尿病或严重的心、肾或肝衰。病人随机接受静注10%甘油溶液(生理盐水为溶媒)或安慰剂(生理盐水)各500 ml,4小时内输完,每天1次,连续6天。结果表明,第1周的死亡人数,甘油治疗组85人中10例(12%),对照组88人中26例(30%),以后直 The authors used double-blind method to investigate the efficacy of intravenous glycerol in elderly patients with hemiparesis after acute stroke. 173 patients with acute cerebral infarction were included in the study within 48 hours of the onset of symptoms and all had hemiparesis, but no possible brainstem stroke, transient ischemic episode, previous sequelae, and other major neurological disorders and Current myocardial infarction, diabetes or severe heart, kidney or liver failure. The patients were randomized to receive 500 ml intravenous 10% glycerol solution (saline as vehicle) or placebo (saline), respectively, and were delivered within 4 hours once daily for 6 days. The results showed that the number of deaths in the first week was 10 (85%) in the glycerol-treated group and 26 (30%) in the 88 control subjects