麻省理工学院研究人员与来自塔夫脱大学的合作者利用工程化大肠杆菌大量生产抗癌药泰索帝的一种关键化合物前体,这些大肠杆菌最初从紫杉树树皮中分离得到。与其他工程化微生物菌株相比,这种工程化细菌产生的泰索帝前体紫杉二烯产率高出一千多倍。这项研究结果发表于2010年10月1 Researchers at MIT and collaborators from Taft University have used mass production of engineered Escherichia coli, a key precursor of the anti-cancer drug taxotere, originally isolated from the bark of yew trees. The engineered bacteria produce taxotere, a taxotere precursor, in excess of 1,000 times more productive than other engineered microbial strains. This study was published on October 1, 2010