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[目的]了解草甘膦职业接触工人肝脏指标检查结果。[方法]采用整群抽样的方法抽取4家草甘膦生产企业进行职业卫生调查和作业场所空气中草甘膦监测。选取草甘膦生产一线工人为接触组(345人),选取同厂不接触草甘膦及其他有毒有害因素的工人为对照组(345人)。对工人进行问卷调查以及健康检查。[结果]工厂作业环境空气中草甘膦质量浓度监测以干燥和包装岗位较高,干燥岗位最高达到94.59 mg/m3,包装岗位最高达到20.68~26.43 mg/m3。接触组胆碱酯酶(Ch E)、丙氨酸转氨酶(ALT)、总胆红素(TBIL)异常率(10.4%、12.5%、11.9%)均高于对照组(4.3%、7.8%、6.1%)(P=0.002、P=0.044、P=0.008)。草甘膦接触工人中,高工龄组肝脏B超异常率(39.6%)高于低工龄组(27.0%)(P=0.014);男工肝脏B超异常率(36.5%)、ALT异常率(16.6%)均高于女工(23.1%、2.9%)(P=0.014,P=0.000),女工Ch E异常率(19.2%)高于男工(6.6%)(P=0.000)。[结论]草甘膦可能会对接触工人的肝脏造成损伤。
[Objective] To understand the result of liver index test of glyphosate-exposed workers. [Method] Four groups of glyphosate producers were sampled by cluster sampling method for occupational health survey and glyphosate monitoring in workplace air. The first-line workers in glyphosate production were selected as the exposure group (345 persons), and the control group (345 persons) was selected as the control group with no exposure to glyphosate and other toxic and harmful factors. Survey workers and health checkups. [Result] The monitoring of the concentration of glyphosate in the air of the working environment of the factory was higher with the drying and packaging positions reaching the highest level of 94.59 mg / m3 and the packing positions up to 20.68-26.43 mg / m3. The abnormal rates of ChE, ALT and TBIL in the exposure group were significantly higher than those in the control group (4.3%, 7.8%, 11.9% 6.1%) (P = 0.002, P = 0.044, P = 0.008). Among glyphosate-exposed workers, the abnormal rate of liver abnormalities (B) was higher in high-service-age group (39.6%) than in lower-service group (27.0%) (P = 0.014) 16.6%) than female workers (23.1%, 2.9%) (P = 0.014, P = 0.000). The abnormal rate of Ch E in female workers was higher than that of male workers (6.6%) (P = 0.000). [Conclusion] Glyphosate may cause damage to the liver of exposed workers.