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干细胞移植技术面临的最大问题就是干细胞的选择和来源。羊膜上皮细胞(AEC)具有向一些三胚层(外胚层、中胚层和内胚层)细胞分化的潜能及类似干细胞的特性,免疫原性低且具有抗炎症作用,移植后无致瘤性和排斥反应。羊膜是产后废弃物,来源丰富,无伦理问题。因此,AEC在干细胞移植及再生医学上有广阔的应用前景,正逐步成为干细胞移植的理想来源。
Stem cell transplantation technology is the biggest problem facing the selection and source of stem cells. Amniotic membrane epithelial cells (AECs) have the potential to differentiate to some of the three germ layers (ectoderm, mesoderm and endoderm) and stem cell-like properties, have low immunogenicity and have anti-inflammatory effects, have no tumorigenicity and rejection after transplantation . Amniotic membrane is a post-natal waste, rich in origin, no ethical issues. Therefore, AEC has broad application prospects in stem cell transplantation and regenerative medicine and is gradually becoming an ideal source of stem cell transplantation.