目的为研究颈椎退行性改变所致的椎动脉型颈椎病建立椎动脉受压的动物模型。方法采用家兔30只经颈前正中入路,在颈椎5、6横突间骨膜下椎动脉内侧植入骨块.术后彩色多普勒、椎动脉造影及CT检查。结果检查结果与临床检查推动脉型颈椎病的特点相同,有特征性血液动力学指标改变及血浆内皮素(ET)的变化。结论本方法制成模型的致压因素确切稳定.对动物损伤小,有利于进一步研究,成功率80.2%. Objective To study the establishment of vertebral artery compression in cervical spondylotic myelopathy caused by cervical degenerative changes. Methods Thirty rabbits were implanted into the medial side of the subperiosteal vertebral artery with transverse approach through the anterior cervical approach with color Doppler, vertebral artery angiography and CT. The results of the examination and clinical examination to promote the characteristics of the same type of cervical spondylosis, there are characteristic changes in hemodynamic indicators and changes in plasma endothelin (ET). Conclusions The pressure-induced factors of the model made by this method are exactly stable, and the damage to animals is small, which is conducive to further study with a success rate of 80.2%.