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目的:对比分析老年与青中年类风湿关节炎临床表现和实验室指标。方法:回顾性对比分析我院2006年1月-2009年12月门诊及住院的43例老年类风湿关节炎(EORA)和89例青中年类风湿关节炎(YORA)的临床表现及实验室指标。结果:EORA组和YORA组性别比(女/男)分别为1.39和2.71(p<0.05)。EORA组和YORA组急性起病分别占60.5%和24.7%(p<0.05)。EORA组患者肩关节受累比例明显高于YORA组(p<0.05),但肘关节、掌指关节、指间关节、踝关节和跖趾关节受累比例明显低于YORA组(p<0.05)。EORA组患者体重下降和肌痛较YORA组常见(p<0.05)。EORA组患者ESR和CRP水平明显高于YORA组(p<0.05),但RF和ANA阳性率明显低于YORA组(p<0.05)。结论:EORA患者和YORA患者在临床表现及实验室检查存在一些明显差异。这提示年龄可能会影响类风湿关节炎疾病的表现形式。
Objective: To compare and analyze the clinical manifestations and laboratory indexes of rheumatoid arthritis in the elderly and adolescent. Methods: A retrospective analysis of clinical manifestations and laboratory findings of 43 elderly rheumatoid arthritis (EORA) and 89 middle-aged adolescent rheumatoid arthritis (YORA) clinics in our hospital from January 2006 to December 2009 was performed. index. Results: The sex ratio (female / male) in EORA and YORA groups was 1.39 and 2.71, respectively (p <0.05). The acute onset rates in EORA and YORA groups were 60.5% and 24.7%, respectively (p <0.05). The proportion of shoulder involvement in EORA group was significantly higher than that in YORA group (p <0.05), but the elbow, metacarpophalangeal joint, interphalangeal joint, ankle joint and metatarsophalangeal joint involvement were significantly lower than those in YORA group (p <0.05). Weight loss and myalgia in the EORA group were more common than those in the YORA group (p <0.05). ESR and CRP levels in EORA group were significantly higher than those in YORA group (p <0.05), but the positive rates of RF and ANA were significantly lower than those in YORA group (p <0.05). Conclusion: There are some significant differences in clinical manifestations and laboratory tests between EORA patients and YORA patients. This suggests that age may affect the manifestation of rheumatoid arthritis disease.