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用强力霉素作为胸膜硬化剂对31例患者进行了胸腔内注射,其中恶性胸腔积液27例,支气管胸膜瘘4例。方法为用28-32号胸管在患侧腋后线第8或9肋间(气胸者在前胸)穿刺引流,待胸液基本消失、肺复张后将强力霉紊500～1000mg加生理盐水30～50ml通过胸管注入胸腔,将胸管夹住,嘱病人转动体位使药物与胸腔充分接触。25例患者注射硬化剂前30分钟通过胸管注射1％利多卡因200～400mg预防疼痛,胸腔积液病人待每天引流量少于100ml可拔掉胸管,其他病人常规应用硬化剂后数小时拔掉胸管,应用硬化剂后平均胸管留置时间为1.8±1.3天。
31 patients underwent intrapleural injection of doxorubicin as pleural sclerotherapy, including 27 cases of malignant pleural effusion and 4 cases of bronchopleural fistula. Method for the use of 28-32 chest tube in the affected side of the posterior axillary line 8 or 9 intercostal space (pneumothorax in the chest) puncture and drainage until the pleural effusion basically disappeared after lung recruitment of strong mildew 500 ~ 1000mg plus physiology Saline 30 ~ 50ml through the chest tube into the chest, the chest tube clamp, instruct patients to turn the body position so full access to drugs and chest. Twenty-five patients received 200-400 mg lidocaine 1% lidocaine 30 minutes before injection of sclerosant to prevent pain. Patients with pleural effusion had to drain the chest tube less than 100 ml per day. Other patients routinely applied sclerotherapy for several hours Unplug the chest tube, the average chest tube retention time after application of 1.8 ± 1.3 days.