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采用~(99m)Tc-甲氧基异丁基异腈(MIBI)示踪剂测定槲皮素磷酸酯钾(PQP)对小鼠心肌营养性血流的影响。实验表明ip PQP 200mg/kg可使小鼠每克心肌~(99m)Tc-MIBI的摄取能力与对照组相比增加55.36％,这一结果表明PQP有增加心肌营养性血流的作用,同时也表明可以用~(99m)Tc-MIBI替代~(36)Rb测定心肌营养性血流。
The effect of quercetin potassium phosphate (PQP) on cardiac nourishing blood flow in mice was determined by ~ (99m) Tc-methoxyisobutylisonitrile (MIBI) tracer. Experiments show that ip PQP 200mg / kg mice per gram of myocardial ~ (99m) Tc-MIBI uptake capacity compared with the control group increased by 55.36%, the results show that PQP increase myocardial nutritional blood flow, but also It is indicated that ~ (99m) Tc-MIBI can be used in place of ~ (36) Rb for the determination of myocardial nutritional blood flow.