本文通过２８例单纯疱疹病毒脑炎（ＨＳＥ）患者分析，研究了几种辅助检查对ＨＳＥ的诊断价值：发现脑电图、脑脊液在病初就有改变，但定位、定性均不确切，可作为早期诊断的参考。脑ＣＴ的“马蹄形”改变为本病所独有，对诊断本病有重要价值，但非所有病例都出现；ＨＳＶ抗原检测在病初即有改变，可作为早期定性诊断的依据。故ＨＳＶ抗原检测配合脑ＣＴ检查，可得到准确的定位、定性诊断 In this paper, 28 cases of herpes simplex virus encephalitis (HSE) in patients with the analysis of several auxiliary examination on the diagnostic value of HSE: EEG found, cerebrospinal fluid in the early disease has changed, but the positioning and qualitative are not exact, can be used as Early diagnosis of reference. Brain CT “horseshoe” change is unique to the disease, the diagnosis of the disease has important value, but not all cases have occurred; HSV antigen test at the beginning of a change that can be used as a basis for early qualitative diagnosis. Therefore, HSV antigen detection with brain CT examination can be accurate positioning, qualitative diagnosis