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随着胃癌诊断技术的进步,位于胃上部的早期胃癌检出率不断提高。根据日本胃癌学会2002年《日本胃癌治疗指南》,位于胃上部的Ⅰa期及直径<2 cm的Ⅰb期早期胃癌可作为行近端胃切除术的适应证。全胃切除术曾因其良好的安全性及根治性被广泛接受,但全胃切除使胃泌素、胃酸和胃蛋白酶等分泌功能消失,影响消化功能,导致病人长期营养不良。近期的一系列研究表明,早期胃癌病人行近
With the progress of gastric cancer diagnosis technology, the detection rate of early gastric cancer located in the upper part of the stomach is increasing. According to the Japan Society of Gastroenterology 2002 Guidelines for the Treatment of Japanese Gastric Cancer, stage Ⅰa and early stage Ⅰb gastric cancer with a diameter of <2 cm located in the upper part of the stomach can be used as indications for proximal gastrectomy. Total gastrectomy has been widely accepted because of its good safety and radical, but the total gastrectomy so that secretion of gastrin, gastric acid and pepsin and other functions disappear, affecting digestive function, leading to long-term malnutrition in patients. A recent series of studies have shown that patients with early gastric cancer are approaching